Article

A novel innate pathogen sensing strategy involving ubiquitination of bacterial surface proteins

2021-10-20

Abstract excerpt

Sensing of pathogens by ubiquitination is critical for maintaining cytosolic sanctity. However, universal ubiquitination targets on bacteria, especially of proteinaceous origin, remain unidentified. Here, we unveil a novel strategy, involving recognition of degron-like motifs for identification of first protein-based ubiquitination substrates on phylogenetically distinct bacteria. Such motifs can form a new class...

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Literature Corpus work: 3f90cc8d-01ae-51d9-8d46-bac57368d383
DOI: 10.1101/2021.10.20.465158

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