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The ubiquitin ligation machinery in the defense against bacterial pathogens

13 Sept 2021

Abstract excerpt

The ubiquitin system is an important part of the host cellular defense program during bacterial infection. This is in particular evident for a number of bacteria including Salmonella Typhimurium and Mycobacterium tuberculosis which-inventively as part of their invasion strategy or accidentally upon rupture of seized host endomembranes-become exposed to the host cytosol. Ubiquitylation is involved in the detection...

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PMID: 34515402
DOI: 10.15252/embr.202152864

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