Article

5hmC and TET2 Dysregulation in Bladder Cancer: Diagnostic and Prognostic Implications

2026-06-05

Abstract excerpt

<title>Abstract</title> <p> BLCA remains a major clinical challenge due to high recurrence rates and the lack of reliable prognostic biomarkers. Since epigenetic dysregulation is a hallmark of urothelial carcinogenesis, we investigated the diagnostic and prognostic potential of 5hmC and TET2, a key regulator of active DNA demethylation. Immunohistochemical analysis of 5hmC and TET2 was performed in 133 BLCA samp...

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Literature Corpus work: 3f563e08-e365-5eb1-b07d-9d5e32fb8a25
DOI: 10.21203/rs.3.rs-9741262/v1

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