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Article

Genome-wide analysis of CpG island methylation in bladder cancer identified TBX2, TBX3, GATA2, and ZIC4 as pTa-specific prognostic markers.

European urology - 1 Jun 2012

Kandimalla Raju, van Tilborg Angela A G, Kompier Lucie C, Stumpel Dominique J P M, Stam Ronald W, Bangma Chris H, Zwarthoff Ellen C

Abstract excerpt

BACKGROUND: DNA methylation markers could serve as useful biomarkers, both as markers for progression and for urine-based diagnostic assays. OBJECTIVE: Identify bladder cancer (BCa)-specific methylated DNA sequences for predicting pTa-specific progression and detecting BCa in voided urine. DESIGN, SETTING, AND PARTICIPANTS: Genome-wide methylation analysis was performed on 44 bladder tumours using the Agilent...

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Source

Identifiers

PMID: 22284968
DOI: 10.1016/j.eururo.2012.01.011

Genes

GATA2
TBX2
TBX3
ZIC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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