Article

Family History Assessment Significantly Enhances Delivery of Precision Medicine in the Genomics Era

2020-01-30

Abstract excerpt

<h4>Background</h4> Family history has traditionally been an essential part of clinical care to assess health risks. However, declining sequencing costs have precipitated a shift towards genomics-first approaches in population screening programs, with less emphasis on family history assessment. We evaluated the utility of family history for genomic sequencing selection. <h4>Methods</h4> We analysed whole genome...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3f4267a0-bb9a-5c71-9a6f-9cbd2356ec2e
DOI: 10.1101/2020.01.29.926139

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Family History Assessment Significantly Enhances Delivery of Precision Medicine in the Genomics EraDOI 10.1101/2020.01.29.926139Read

Family history: Still relevant in the genomics eraSemantic proximity Read

Genomics in primary care practice.Semantic proximity Read

Streamlining Inherited Cancer Identification via an EMR-Integrated Risk Assessment Platform: A Nonrandomized Clinical Trial.Semantic proximity Read

Assessing disease risk in genome-wide association studies using family history.Semantic proximity Read

Prospective comparison of family medical history with personal genome screening for risk assessment of common cancers.Semantic proximity Read

Importance of family history and indications for genetic testing.Semantic proximity Read

The Crucial Role of Hereditary Cancer Panel Testing in Unaffected Individuals with a Strong Family History of Cancer: A Retrospective Study of a Cohort of 103 Healthy SubjectsSemantic proximity Read

Family history and genetic risk score combined to guide cancer risk stratification: A prospective cohort study.Semantic proximity Read

Family history in public health practice: a genomic tool for disease prevention and health promotion.Semantic proximity Read

Family history and improving health.Semantic proximity Read

Systematic comparison of family history and polygenic risk across 24 common diseasesSemantic proximity Read

A framework for integrated clinical risk assessment using population sequencing dataSemantic proximity Read