Article

Reverse Transcriptase PCR Amplification of EWS/FLI-1 Fusion Transcripts as a Diagnostic Test for Peripheral Primitive Neuroectodermal Tumors of Childhood

1993-09-01

Abstract excerpt

The peripheral primitive neuroectodermal tumors (pPNETs) of childhood, including Evving's sarcoma, peripheral neuroepithelioma, and Askin's tumor, often present significant diagnostic challenges for the anatomic pathologist. One consistent feature of these tumors is the presence of the t(11;22)(q24;q12) in tumor cells, and this translocation has been useful as a marker for this group of tumors. The recent cloning...

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Literature Corpus work: 3f2610b5-2bb0-5a43-affb-748ebf6a1a35
DOI: 10.1097/00019606-199309000-00002

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