Article
Biphenotypic sarcomas with myogenic and neural differentiation express the Ewing's sarcoma EWS/FLI1 fusion gene.
Cancer research - 15 Mar 1995
Sorensen P H, Shimada H, Liu X F, Lim J F, Thomas G, Triche T J
Abstract excerpt
Accurate diagnosis of primitive childhood sarcomas continues to be a formidable problem because these malignancies generally demonstrate very little morphological evidence of their tissue of origin. One of these tumor classes, the Ewing's sarcoma family of peripheral primitive neuroectodermal tum...
Topics
- Adolescent
- Adult
- Base Sequence
- Cell Differentiation
- Child
- DNA-Binding Proteins
- Gene Expression
- Heterogeneous-Nuclear Ribonucleoproteins
- Humans
- Infant
- Molecular Sequence Data
- MyoD Protein
- Neuroectodermal Tumors, Primitive
- Nuclear Proteins
- Phenotype
- Proto-Oncogene Protein c-fli-1
- Proto-Oncogene Proteins
- RNA-Binding Protein EWS