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Prediction of Prophylactic Response to Lithium in Bipolar Disorder Using Acute Antidepressant Non-Response to Ketamine: A Scoping Review

2025-09-29

Abstract excerpt

Lithium remains the first choice for long-term prophylaxis of mood episodes in bipolar disorder (BD), but only 30% of patients will respond, and there is no reliable method by which to predict treatment response. Ketamine is a rapid antidepressant therapy which ostensibly yields greater results in patients with clinical phenotypes that are classically associated with lithium non-response. Thus, we hypothesized an...

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Literature Corpus work
3f0275cf-b5b5-5778-bc6c-4df103e5c083
DOI
10.20944/preprints202509.2378.v1
Open publication

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Prediction of Prophylactic Response to Lithium in Bipolar Disorder Using Acute Antidepressant Non-Response to Ketamine: A Scoping ReviewDOI 10.20944/preprints202509.2378.v1
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