Article

Genomic landscape of<i>TP53</i>-mutated myeloid malignancies

2023-01-11

Abstract excerpt

TP53 -mutated myeloid malignancies are most frequently associated with complex cytogenetics. The presence of complex and extensive structural variants complicates detailed genomic analysis by conventional clinical techniques. We performed whole genome sequencing of 42 AML/MDS cases with paired normal tissue to characterize the genomic landscape of TP53 -mutated myeloid malignancies. The vast majority of cases had...

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Literature Corpus work: 3ea64cea-5c84-5e2c-b781-3798d78ac63d
DOI: 10.1101/2023.01.10.23284322

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