Article

Design and In Silico Validation of a Novel Multi-Epitopes Subunit Vaccine Candidate against Lassa Virus Using Reverse Vaccinology Approach

2025-11-26

Abstract excerpt

<title>Abstract</title> Lassa fever, caused by the Lassa virus (LASV), remains a significant public health threat in West Africa, characterised by annual outbreaks, substantial morbidity, and high case-fatality rates in hospitalized patients. The natural immune response to LASV is often marked by a delayed and weak neutralising antibody response, with survival correlating more strongly with robust cell-media...

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Literature Corpus work: 3e9652ea-537c-5ad5-9230-3286fbb1259c
DOI: 10.21203/rs.3.rs-7860035/v1

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