Article
Reverse Vaccinology and Immune Simulation of a Novel Multiepitope Vaccine Targeting <em>Brucella </em>Virulence
2025-12-03
Abstract excerpt
<h4>Background: </h4> /Objectives: Brucella is a major global One Health threat, causing an estimated 2.1 million human infections and substantial livestock losses annually, with no vaccine currently available for humans, underscoring the urgent need for a safe and effective vaccine. <h4>Methods:</h4> Employing a reverse vaccinology approach, a novel 175-mer multiepitope vaccine (Mvax) targeting Brucella FrpB was...
Topics
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- Bacteriophages and microbial interactions
- Brucella: diagnosis, epidemiology, treatment
- Hepatitis B Virus Studies
- Monoclonal and Polyclonal Antibodies Research
- Pneumonia and Respiratory Infections
- Toxin Mechanisms and Immunotoxins
- vaccines and immunoinformatics approaches
- Viral Infections and Outbreaks Research
Identifiers and source
- Literature Corpus work
- 24a74406-d3a3-5008-937d-4325ee82484e
- DOI
- 10.20944/preprints202512.0403.v1
