Back to search

Article

Primary Splenic Histiocytic Sarcoma Associated with Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome): A Case Report of Next-Generation Sequency Involving FLT3, NOTCH2, and KMT2A Mutations

2021-01-18

Abstract excerpt

<title>Abstract</title> <p>BackgroundHistiocytic sarcoma (HS) is a very rare monocyte/macrophage-derived hematopoietic system tumor with a poor prognosis whose diagnosis is pathologically challenging due to its extreme rarity and histological overlap with various mimicking entities in which histiocytes also predominate.Case PresentationWe report the case of a 33-year-old male patient with hemophagocytic lymphohis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3e8b4574-1af3-52f8-8e92-fc2616b27c8a
DOI
10.21203/rs.3.rs-147660/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Primary Splenic Histiocytic Sarcoma Associated with Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome): A Case Report of Next-Generation Sequency Involving&nbsp;FLT3, NOTCH2,&nbsp;and&nbsp;KMT2A&nbsp;MutationsDOI 10.21203/rs.3.rs-147660/v1
Primary splenic histiocytic sarcoma associated with hemophagocytic lymphohistiocytosis: A case report and review of literature of next-generation sequencing involving FLT3, NOTCH2, and KMT2A mutations.Semantic proximity
Case report: Targeting the PD-1 receptor and genetic mutations validated in primary histiocytic sarcoma with hemophagocytic lymphohistiocytosis.Semantic proximity
Extranodal Histiocytic Sarcoma: A Clinicopathologic Study of Two Cases and Literature Review.Semantic proximity
Clinico-radiological features and next generation sequencing of pulmonary epithelioid hemangioendothelioma: A case report and review of literature.Semantic proximity
A Rare Cohesive Cytomorphology in Primary Histiocytic Sarcoma of Bone Marrow with PD-L1 Expression: A case report and systemic literature reviewSemantic proximity
Current Updates on Classification, Diagnosis and Treatment of Hemophagocytic Lymphohistiocytosis (HLH)Semantic proximity
Hemophagocytic Lymphohistiocytosis caused by GATA2 deficiency : cases reportSemantic proximity
Erdheim-Chester Disease with BRAF V600E Mutation and a Concomitant Myeloid Malignancy Sharing NRAS and IDH2 Mutations.Semantic proximity
Adult Lymphoma-Associated Hemophagocytic Lymphohistiocytosis: Clinical Features, Diagnostic Challenges, and Treatment Outcomes—A 24-Year Multi-Center AnalysisSemantic proximity
Histiocytosis.Semantic proximity
Spectrum of histiocytic neoplasms associated with diverse haematological malignancies bearing the same oncogenic mutation.Semantic proximity
Histiocytosis with STEAP3-Associated Anemia and Type 4 HemochromatosisSemantic proximity
Select a neighboring publication to make it the new centre.