Article

Humanized CAR T cells targeting p95HER2

2022-05-20

Abstract excerpt

Redirection of T lymphocytes against tumor-associated or tumor-specific antigens, via bispecifc T cells engagers (BiTEs) or chimeric antigen receptors (CARs), is a successful therapeutic strategy against certain hematologic malignancies. In contrast, so far it has failed against solid tumors. Given the scarcity of tumor-specific antigens, the vast majority of BiTEs and CAR Ts developed to date have been directed a...

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Literature Corpus work: 3e4cd621-f947-5ca7-9c6c-44382533d182
DOI: 10.1101/2022.05.20.492812

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