Article

DAGM: a novel modelling framework to assess the risk of HER2-negative breast cancer based on germline rare coding mutations

2021-01-09

Abstract excerpt

<h4>Background</h4> Breast cancers can be divided into HER2-negative and HER2-positive subtypes according to the status of HER2 gene. Despite extensive studies connecting germline mutations with possible risk of HER2-negative breast cancer, the main category of breast cancer, it remains challenging to accurately assess its potential risk and to understand the potential mechanisms. <h4>Methods</h4> We developed a n...

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Literature Corpus work: 3e37d132-47c9-5cf3-a767-603b127d74c5
DOI: 10.1101/2021.01.05.21249253

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