Article
Evidence of in vivo prophage induction during Clostridium difficile infection.
Applied and environmental microbiology - 1 Nov 2012
Meessen-Pinard Mathieu, Sekulovic Ognjen, Fortier Louis-Charles
Abstract excerpt
Prophages contribute to the evolution and virulence of most bacterial pathogens, but their role in Clostridium difficile is unclear. Here we describe the isolation of four Myoviridae phages, ΦMMP01, ΦMMP02, ΦMMP03, and ΦMMP04, that were recovered as free viral particles in the filter-sterilized stool supernatants of patients suffering from C. difficile infection (CDI). Furthermore, identical prophages were found...
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