Article

Production of Noncapped Genomic RNAs is Critical to Sindbis Virus Disease and Pathogenicity

2020-06-11

Abstract excerpt

<h4>ABSTRACT</h4> Alphaviruses are positive-sense RNA viruses that utilize a 5’ cap structure to facilitate translation of viral proteins and to protect the viral RNA genome. Nonetheless, significant quantities of viral genomic RNAs that lack a canonical 5’ cap structure are produced during alphaviral replication and packaged into viral particles. However, the role/impact of the noncapped genomic RNA (ncgRNA) dur...

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Literature Corpus work: 3d8efafc-d995-52b7-a503-f6e261983159
DOI: 10.1101/2020.06.11.145847

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