Identification and Characterization of Sindbis Virus RNA-Host Protein Interactions

Abstract excerpt

ABSTRACT Arthropod-borne viruses, such as the members of the genus Alphavirus , are a significant concern to global public health. As obligate intracellular pathogens, RNA viruses must interact with the host cell machinery to establish and complete their life cycles. Despite considerable efforts to define the host-pathogen interactions essential for alphaviral replication, an unbiased and inclusive assessment of...

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