Article

A personalized 14-3-3 disease-targeting workflow yields repositioning drug candidates

2025-01-23

Abstract excerpt

<title>Abstract</title> <p>Rare diseases typically evade the application of the standard drug discovery and development pipeline due to their understudied molecular etiology and the small market size. Here, we report a rare disease-directed workflow that rapidly studies the molecular features of the disorder, establishes a high-throughput screening (HTS) platform, and conducts an HTS of thousands of approved drug...

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Literature Corpus work: 3c96b7d1-889e-5f01-9dbf-bc74657117ea
DOI: 10.21203/rs.3.rs-5842389/v1

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