Article

The effects of analgesics and local anesthetics on gene transcription mediated by NFATc2 and Sp1 in pancreatic carcinoma

2019-09-16

Abstract excerpt

<h4>Background: </h4> Pancreatic adenocarcinoma is one of the most lethal cancers worldwide with very poor long-term survival. The treatment of choice next to chemotherapy or radiation treatment is surgical removal of the tumor. However, medication, surgery, and perioperative immunosuppression induce the constitutive activation of important signaling pathways and change the regulation of transcription factors, whi...

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Literature Corpus work: 3c8d1c14-1fbf-5c2f-93fb-cbd39a140cfc
DOI: 10.21203/rs.2.14445/v1

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