Article

Coiled Coil Crosslinked Alginate Hydrogels Dampen Macrophage-Driven Inflammation

2021-11-04

Abstract excerpt

<h4>ABSTRACT</h4> Alginate hydrogels are widely used for tissue engineering and regenerative medicine due to their excellent biocompatibility. A facile and commonly used strategy to crosslink alginate is the addition of Ca 2+ that leads to hydrogelation. However, extracellular Ca 2+ is a secondary messenger in activating inflammasome pathways following physical injury or pathogenic insult leading to persistent...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3c826a37-cc21-5a0a-9967-b1ea124ad9eb
DOI: 10.1101/2021.11.01.466776

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Coiled Coil Crosslinked Alginate Hydrogels Dampen Macrophage-Driven InflammationDOI 10.1101/2021.11.01.466776Read

Microbiome-Responsive Hydrogels: From Biological Cues to Smart BiomaterialsSemantic proximity Read

Novel Hydrogels for Drug Delivery and Regenerative Medicine: Advances, Engineering Strategies, and Clinical TranslationSemantic proximity Read

An orally administered peptide hydrogel disentangles immune-microbiota crosstalk for long-term ulcerative colitis therapySemantic proximity Read

Microencapsulation of mesenchymal stromal cells in covalent alginate hydrogels for cell therapySemantic proximity Read

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage PolarizationSemantic proximity Read

Towards antimicrobial yet bioactive Cu-alginate hydrogels.Semantic proximity Read

Physical confinement in alginate cryogels determines macrophage polarization to a M2 phenotype by regulating a STAT-related mRNA transcription pathway.Semantic proximity Read

Influence of Physico-Chemical Properties of Two Lipoxin Emulsion-Loaded Hydrogels on Pre-Polarized Macrophages: A Comparative AnalysisSemantic proximity Read

All-Natural Immunomodulatory Bioadhesive Hydrogel Promotes Angiogenesis and Diabetic Wound Healing by Regulating Macrophage Heterogeneity.Semantic proximity Read

Multifunctional Hydrogel with Mild Photothermal Properties Enhances Diabetic Wound Repair by Targeting MRSA Energy MetabolismSemantic proximity Read

In vivo screening of hydrogel library using cellular barcoding identifies biomaterials that mitigate host immune responses and fibrosisSemantic proximity Read

Chemical, physical and biological properties of alginates and their biomedical implicationsSemantic proximity Read