Article

Gangliosides Modulate the Secretion of Extracellular Vesicles and Their Misfolded Protein Cargo

2025-04-04

Abstract excerpt

Gangliosides are glycosphingolipids that play an integral role in cell signaling and provide neuroprotection. While present on extracellular vesicles (EVs) – key mediators of intercellular communication – their role in EV biogenesis remains unclear. Here, we identify gangliosides, both endogenously synthesized and exogenously administered, as key modulators of EV biogenesis, with the specific composition of their...

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Literature Corpus work: 3c6606b2-66c4-5895-ba5d-f5f4315890cf
DOI: 10.1101/2025.04.03.647108

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