Rapid, highly specific and sensitive detection of human adenovirus using multiple cross displacement amplification coupled with CRISPR-Cas12a-based detection

Abstract excerpt

• A novel diagnositc method based on isothermal multiple cross displacement amplification and CRISPR-cas12-based detection was devised for detection of HAdV-3 and HAdV-7. • The new approach exhibited unique advantages of simplicity, speed, and accuracy. • The new nearly equipment-free technique makes it a valuable diagnostic tool for timely diagnosis and intervention of HAdV-3 and HAdV-7 infection. Human adenoviru...

Topics

Open a Topic to create a Post that cites this publication.

• CRISPR and Genetic Engineering
• Viral Infections and Immunology Research
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

3c1a724c-d163-533d-89e8-d1e65ae368f3

DOI

10.1016/j.talo.2025.100462