Article

Localization of protoporphyrin IX in glioma patients with paired stimulated Raman histology and two-photon excitation fluorescence microscopy

2022-12-22

Abstract excerpt

<title>Abstract</title> <p>Fluorescence guidance is widely utilized to improve the precision of cancer surgery. 5-aminolevulinic acid, the most widely used fluorophore in glioma surgery, is thought to cause selective accumulation of fluorescent protoporphyrin IX (PpIX) in tumor cells. 5-aminolevulinic acid is highly specific for densely tumor-infiltrated tissue but less effective for visualizing the tumor periphe...

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Literature Corpus work: 3bab21d0-ddf2-5a63-984a-c5888f9a43c9
DOI: 10.21203/rs.3.rs-1519287/v1

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