Article

Identification of cell cycle dependent methotrexate resistance in placenta site trophoblastic tumors

2020-04-28

Abstract excerpt

<h4>Background: </h4> The purpose is to study the mechanism of chemotherapy resistance in Placental site trophoblastic tumor(PSTT).Methods We established PSTT cell lines by primary culture of a surgically resected PSTT tissues and identified the expression of immune-phenotype markers(HLA-G, β-catenin, CD146, Muc4, hPL, hCG) by immunofluorescence. We measured the IC50 value of methotrexate(MTX), etoposide(VP-16), a...

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Literature Corpus work: 3b54bf56-6042-5451-8e26-78e4c841c09f
DOI: 10.21203/rs.3.rs-24085/v1

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