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Article

Cisplatin Resistance in Testicular Germ Cell Tumors: Current Challenges from Various Perspectives

17 Jun 2020

Abstract excerpt

Testicular germ cell tumors share a marked sensitivity to cisplatin, contributing to their overall good prognosis. However, a subset of patients develop resistance to platinum-based treatments, by still-elusive mechanisms, experiencing poor quality of life due to multiple (often ineffective) interventions and, eventually, dying from disease. Currently, there is a lack of defined treatment opportunities for these...

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PMID: 32560427
DOI: 10.3390/cancers12061601

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