Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole transcriptome analysis of gestational trophoblastic neoplasms reveals altered PI3K signaling pathway in epithelioid trophoblastic tumor.

Gynecologic oncology - 1 Apr 2020

Cho Eun Jeong, Chun Sung-Min, Park Hwan, Sung Chang Ohk, Kim Kyu-Rae

Abstract excerpt

OBJECTIVE: Genomic characteristics of gestational trophoblastic neoplasm (GTN) are mostly unknown. This study reveals the molecular features of malignant GTN, including choriocarcinoma (CC), epithelioid trophoblastic tumor (ETT), and placental site trophoblastic tumor (PSTT), by whole transcriptome sequencing analysis. METHODS: Data obtained from the total RNA sequencing of 2 CC, 4 ETT, and 4 PSTT were evaluated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B7-H1 Antigen
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Choriocarcinoma

Share to Class I Phosphatidylinositol 3-Kinases

Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins c-akt

Share to Sequence Analysis, RNA

Share to TOR Serine-Threonine Kinases

Source

Identifiers

PMID: 31954539
DOI: 10.1016/j.ygyno.2019.09.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole transcriptome analysis of gestational trophoblastic neoplasms reveals altered PI3K signaling pathway in epithelioid trophoblastic tumor.PMID 31954539Read ↗

Molecular analyses of chorionic-type intermediate trophoblastic lesions: Atypical placental site nodules are closer to placental site nodules than epithelioid trophoblastic tumorsSemantic proximity Read ↗

Single-cell and spatial transcriptomics reveal alterations in trophoblasts at invasion sites and disturbed myometrial immune microenvironment in placenta accreta spectrum disordersSemantic proximity Read ↗

Identification of microRNA signature in the progression of gestational trophoblastic diseaseSemantic proximity Read ↗

Molecular Basis of Gestational Trophoblastic DiseasesSemantic proximity Read ↗

PD‐L1, B7‐H3 and VISTA are highly expressed in gestational trophoblastic neoplasiaSemantic proximity Read ↗

Next-Generation Sequencing Panel Analysis of Clinically Relevant Mutations in Circulating Cell-Free DNA from Patients with Gestational Trophoblastic Neoplasia: A Pilot Study.Semantic proximity Read ↗

Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrumSemantic proximity Read ↗

Down-regulated long non-coding RNA PVT1 contributes to gestational diabetes mellitus and preeclampsia via regulation of human trophoblast cellsSemantic proximity Read ↗

Ovarian Intermediate Trophoblastic Tumors: Genotyping Defines a Distinct Category of Nongestational Tumors of Germ Cell Type.Semantic proximity Read ↗

Trophoblast Cell Subtypes and Dysfunction in the Placenta of Individuals with Preeclampsia Revealed by Single-Cell RNA SequencingSemantic proximity Read ↗

Molecular Basis of Hydatidiform Moles – A Systematic ReviewSemantic proximity Read ↗

Twist1 is involved in trophoblast syncytialization by regulating GCM1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.