Article

Polygenic risk scores for asthma and allergic disease associate with COVID-19 severity in 9/11 responders

2022-08-30

Abstract excerpt

<h4>Background</h4> Genetic factors contribute to individual differences in the severity of coronavirus disease 2019 (COVID-19). A portion of genetic predisposition can be captured using polygenic risk scores (PRS). Relatively little is known about the associations between PRS and COVID-19 severity or post-acute COVID-19 in community-dwelling individuals. <h4>Methods</h4> Participants in this study were 983 World...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3b23eb84-dd13-5ff5-910a-cda5bc963b3d
DOI: 10.1101/2022.08.30.22279383

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Polygenic risk scores for asthma and allergic disease associate with COVID-19 severity in 9/11 respondersDOI 10.1101/2022.08.30.22279383Read

Assessing the potential of polygenic scores to strengthen medical risk prediction models of COVID-19.Semantic proximity Read

Severe COVID-19 disease is associated with genetic factors affecting plasma ACE2 receptor and CRP concentrations.Semantic proximity Read

Allergic asthma and type-2 immunity reduce COVID-19 severitySemantic proximity Read

Allergic disease as a causal protective factor for severe covid-19: a multivariable mendelian randomization studySemantic proximity Read

Uncovering associations between pre-existing conditions and COVID-19 Severity: A polygenic risk score approach across three large biobanks.Semantic proximity Read

Genetic Causal Correlations between Allergic Diseases and COVID-19: A Systematic Two-Sample and Bidirectional MR StudySemantic proximity Read

Genetic Association of Allergic Diseases with COVID-19 Susceptibility, Severity and Hospitalization Due to COVID-19: A Bidirectional Mendelian Randomization StudySemantic proximity Read

Genetic causal correlations between allergic diseases and COVID-19: A systematic two-sample and bidirectional MR studySemantic proximity Read

Development and validation of a clinical and genetic model for predicting risk of severe COVID-19.Semantic proximity Read

Genetic Risk and Chronic Obstructive Pulmonary Disease Independently Predict the Risk of Incident Severe COVID-19.Semantic proximity Read

Progresses on genetic susceptibility of COVID-19.Semantic proximity Read

Genomic analysis of severe COVID-19 considering or not asthma comorbidity: GWAS insights from the BQC19 cohort.Semantic proximity Read