Article

A portable molecular laboratory for rapid genotyping in the field: application to sickle cell disease

2026-05-12

Abstract excerpt

<h4>Background</h4> Sickle cell disease (SCD) is the most common recessive genetic disorder, caused by pathogenic variants of the HBB gene. SCD is associated with a range of clinical manifestations, including vaso-occlusive crises, infections, and severe anaemia, which contribute to increased morbidity and mortality. The frequency of pathogenic alleles is high in Sub-Saharan African countries, with heterozygous...

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Literature Corpus work: 3adcde03-a0fa-5edd-9213-b7ed29bb2168
DOI: 10.64898/2026.05.05.26352080

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