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In mice and humans, the brain’s blood vessels mature postnatally to acquire barrier and contractile properties

2021-05-17

Abstract excerpt

The brain dense vascular network is essential for distributing oxygen and nutrients to neural cells. The network develops during embryogenesis and leads to the formation of the endothelial blood-brain barrier (BBB). This barrier is surrounded by mural cells (pericytes and vascular smooth muscle cells (VSMCs)) and fibroblasts. Here, we compared the molecular and functional properties of brain vascular cells on post...

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Literature Corpus work
3ab43d30-5d5d-5310-a75c-990627206d05
DOI
10.1101/2021.05.17.444486
Open publication

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In mice and humans, the brain’s blood vessels mature postnatally to acquire barrier and contractile propertiesDOI 10.1101/2021.05.17.444486
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