Back to search

Article

Comprehensive analysis of DNA methylation and gene expression reveals specific predictive biomarkers for renal cell carcinoma

2020-04-07

Abstract excerpt

<title>Abstract</title> <p>Background We aimed to identify methylation-driven genes (MDGs) and predict the prognosis of clear cell renal cell carcinoma (ccRCC) based on several cohorts with high-throughput data.Methods The transcriptome profiles, 450K methylated data and corresponding clinical information were extracted from the cancer genome atlas (TCGA) database. MethylMix package was used to screen aberrant me...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3ab31e35-77a4-53ce-bf2d-2b221354abb2
DOI
10.21203/rs.3.rs-20244/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Comprehensive analysis of DNA methylation and gene expression reveals specific predictive biomarkers for renal cell carcinomaDOI 10.21203/rs.3.rs-20244/v1
Molecular Characterization, Clinical Significance, Tumor Microenvironment Association and Drug Susceptibility of DNA Methylation-Driven Genes in Renal Cell CarcinomaSemantic proximity
Identifying prognostic biomarkers based on aberrant DNA methylation in kidney renal clear cell carcinomaSemantic proximity
Identification of a novel methylation gene sites signature to predict prognosis in kidney renal papillary cell carcinoma by comprehensive profilingSemantic proximity
A methylomics-correlated nomogram predicts the recurrence free survival risk of kidney renal clear cell carcinomaSemantic proximity
Integrative Analysis of DNA Methylation Identified 12 Signature Genes Specific to Metastatic ccRCCSemantic proximity
A Gene Signature of Survival Prediction for Kidney Renal Cell Carcinoma by Multi-Omic Data Analysis.Semantic proximity
Identification of a m6A RNA methylation regulators-based signature for predicting the prognosis of clear cell renal carcinomaSemantic proximity
Predictive value of m1A-related genes in kidney renal clear cell carcinomaSemantic proximity
A Newly Defined m7G-Related Gene Signature for Overall Survival Prognosis of Kidney Renal Clear Cell CarcinomaSemantic proximity
Identification of methylation-driven genes related to the prognosis of papillary renal cell carcinoma: a study based on The Cancer Genome AtlasSemantic proximity
Identification and validation of a DNA methylation-driven gene-based prognostic model for clear cell renal cell carcinomaSemantic proximity
Multi-omics comprehensive analysis of renal clear cell carcinoma to distinguish subtypes with different molecular characterizations and therapeutic strategiesSemantic proximity
Select a neighboring publication to make it the new centre.