Article

Prediction of Deleterious nsSNPs Causing CHARGE Syndrome Associated with the CHD7 Protein using Computational Approaches

2021-02-26

Abstract excerpt

The Chromo domain helicase DNA binding protein 7 (CHD7) is also known as ATP-dependent helicase CHD7, in humans, the CHD7 gene encodes it. Heterozygous mutations in this protein cause aggregation and has been determined to have an adverse role in causing CHARGE syndrome. Non-synonymous single nucleotide polymorphism (nsSNP) analysis tends to be deleterious of the protein yet to be employed with computational metho...

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Literature Corpus work: 3a73ce56-2c22-553e-826c-965cf3cfa9d9
DOI: 10.21203/rs.3.rs-233256/v1

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