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Rejuvenation of Tissue Stem Cells by Intrinsic and Extrinsic Factors

31 Dec 2021

Abstract excerpt

Stem cell therapies, including stem cell transplantation and rejuvenation of stem cells in situ, are promising avenues for tackling a broad range of diseases. Stem cells can both self-renew and differentiate into other cell types, and play a significant role in the regulation of tissue homeostasis and regeneration after cell degeneration or injury. However, stem cell exhaustion or dysfunction increases with age...

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PMID: 35303745
DOI: 10.1093/stcltm/szab012

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