Article

Enhancement of Tryptic Peptide Signals from Tissue Sections using MALDI IMS Post-ionization (MALDI-2)

2021-01-29

Abstract excerpt

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows for highly multiplexed, unlabeled mapping of analytes from tissue sections. However, further work is needed to improve sensitivity and depth of coverage for protein and peptide IMS. Laser-based post-ionization MALDI-2 has been shown to increase sensitivity for several molecular classes but thus far this has not been reported f...

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Literature Corpus work: 3a5850f3-5b58-58b1-b6e3-7d20f2744b10
DOI: 10.26434/chemrxiv.13483302.v3

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