Article

Single Nucleus Sequencing of Human Colon Visceral Smooth Muscle Cells, PDGFRα Cells, and Interstitial Cells of Cajal

2022-04-14

Abstract excerpt

<h4>Background and Aims</h4> Smooth muscle cells (SMCs), Interstitial cells of Cajal (ICCs), and PDGFRα+ cells (PαCs) form a functional syncytium in the bowel known as the ‘SIP syncytium’. The SIP syncytium works in concert with the enteric nervous system (ENS) to coordinate bowel motility. However, our understanding of individual cell types that form this syncytium and how they interact with each other remains l...

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Literature Corpus work: 3a541061-c9e8-58e4-9882-44fbe779916f
DOI: 10.1101/2022.04.14.488224

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