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Article

scRNA-Seq Reveals New Enteric Nervous System Roles for GDNF, NRTN, and TBX3

1 Jan 2021

Abstract excerpt

BACKGROUND AND AIMS: Bowel function requires coordinated activity of diverse enteric neuron subtypes. Our aim was to define gene expression in these neuron subtypes to facilitate development of novel therapeutic approaches to treat devastating enteric neuropathies, and to learn more about enteric nervous system function. METHODS: To identify subtype-specific genes, we performed single-nucleus RNA-seq on adult...

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Share to Gastrointestinal motility and disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33444816
DOI: 10.1016/j.jcmgh.2020.12.014

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