Back to search

Article

Low-Dose Radiation Effects on the Substantia Nigra in Swine: Insights into Parkinson’s Disease Biomarkers

2025-05-16

Abstract excerpt

<title>Abstract</title> <p>Idiopathic Parkinson’s Disease (iPD) is a neurodegenerative disorder influenced by genetic and environmental factors, including ionizing radiation. While high-dose radiation (HDR) is linked to neuroinflammation and neuronal degeneration, the effects of low-dose radiation (LDR) remain unclear. This study examined the impact of acute total-body LDR (1.79 Gy) on the substantia nigra (SN) o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3a12f2cc-fa34-5017-ac7f-26ffba61cebd
DOI
10.21203/rs.3.rs-6558308/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Low-Dose Radiation Effects on the Substantia Nigra in Swine: Insights into Parkinson’s Disease BiomarkersDOI 10.21203/rs.3.rs-6558308/v1
Low-dose radiation decreases Lrrk2 levels in the striatum of large mammalian brains: New venues to treat Parkinson's disease?Semantic proximity
Deciphering the Metabolic Shifts in The Hippocampus of Mice Subjected to Near Low Dose Radiation: Insights from Metabolomics and Integrated Multi-omicsSemantic proximity
Low-dose ionising radiation exerts effects comparable to MPTP through alterations in locomotor activity, oxidant/antioxidant status and mitochondrial homeostasis in zebrafish embryosSemantic proximity
High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations.Semantic proximity
Non-ablative disease-modifying effects of magnetic resonance-guided focused ultrasound in neuromelanin-producing parkinsonian rodentsSemantic proximity
Long-Term Sex- and Genotype-Specific Effects of 56Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice.Semantic proximity
Pulsed Telecommunication Signals of Non-ionizing Radiation Affect Amyloid Precursor Protein and α-Synuclein Metabolism in Non-neural Human CellsSemantic proximity
Mobile phone electromagnetic radiation affects Amyloid Precursor Protein and α-synuclein metabolism in SH-SY5Y cellsSemantic proximity
Select a neighboring publication to make it the new centre.