Article
High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations.
International journal of molecular sciences - 10 Feb 2023
Hinshaw Robert G, Schroeder Maren K, Ciola Jason, Varma Curran, Colletti Brianna, Liu Bin, Liu Grace Geyu, Shi Qiaoqiao, Williams Jacqueline P, O'Banion M Kerry, Caldarone Barbara J, Lemere Cynthia A
Abstract excerpt
Whole-body exposure to high-energy particle radiation remains an unmitigated hazard to human health in space. Ongoing experiments at the NASA Space Radiation Laboratory and elsewhere repeatedly show persistent changes in brain function long after exposure to simulations of this unique radiation environment, although, as is also the case with proton radiotherapy sequelae, how this occurs and especially how it...
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