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Article

Decreased Hypothalamic Thyrotropin-Releasing Hormone Gene Expression in Patients with Nonthyroidal Illness

1997-12-01

Abstract excerpt

Changes in hypothalamus-pituitary-thyroid function occur in patients with a variety of illnesses and are referred to as the euthyroid sick syndrome or nonthyroidal illness (NTI). In NTI, serum concentrations of T3 decrease to low, or even undetectable, levels without giving rise to elevated concentrations of TSH. We hypothesized that decreased activity of TRH-producing cells in the paraventricular nucleus (PVN) co...

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Identifiers and source

Literature Corpus work
390e796c-67a7-55bf-bfda-2e6061ae6311
DOI
10.1210/jc.82.12.4032
Open publication

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