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Article

Altered thyroid axis function in Lewis rats with genetically defective hypothalamic CRH/VP neurosecretory cells.

Endocrine research - 1 Nov 1997

Whitnall M H, Smallridge R C

Abstract excerpt

Lewis rats display hyporesponsive hypothalamo-pituitary-adrenocortical (HPA) axes, overproduction of cytokines, and susceptibility to inflammatory disease. The Lewis corticotropin-releasing hormone (CRH) neurosecretory system contains normal numbers of vasopressin (VP)-deficient axon varicosities, but abnormally sparse VP-containing varicosities in the external zone of the median eminence, compared to the...

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Identifiers

PMID: 9430824
DOI: 10.1080/07435809709031863

Genes

CRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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