Thyroid Hormone and Estrogen Regulate Brain Region-Specific Messenger Ribonucleic Acids Encoding Three Gonadotropin-Releasing Hormone Genes in Sexually Immature Male Fish, Oreochromis niloticus*

Abstract excerpt

The present study was undertaken to determine whether T3, estrogen, and 11-ketotestosterone could alter a specific population of GnRH-containing neurons, as indicated by a change in messenger RNA (mRNA) levels in sexually immature male tilapia, Oreochromis niloticus. Two weeks after castration, fish were assigned to four treatment groups. One group served as the control (sesame oil); a single ip injection of (T3;...

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