Article
Magnetogenetic closed-loop reduction of seizure activity in a rat model of epilepsy
2022-08-22
Abstract excerpt
On-demand neurostimulation has shown success in epilepsy patients with pharmacoresistant seizures. Seizures produce magnetic fields that can be recorded using magnetoencephalography. We developed a new closed-loop approach to control seizure activity based on magnetogenetics using the electromagnetic perceptive gene (EPG) that encodes a protein that responds to magnetic fields. The EPG transgene was expressed in i...
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Identifiers and source
- Literature Corpus work
- 38fa7035-31a6-5f0e-ad4e-2a09a4094202
- DOI
- 10.1101/2022.08.19.504501