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Multi-omics analysis identifies lactylation-mediated immune biomarkers in esophageal cancer

2025-08-25

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<title>Abstract</title> <p><bold>Objectives:</bold> This study aimed to investigate the prognostic value of lactate metabolism-related genes (LMRGs) in esophageal cancer (EC), exploring their roles in tumor microenvironment (TME) remodeling, immunotherapy response, and potential therapeutic targeting. <bold>Methods:</bold> Multi-omics analysis integrated bulk RNA-seq (TCGA, GEO) and single-cell RNA-seq (scRNA-seq...

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Literature Corpus work
8bd2609a-555d-5a28-9067-f3f82b8932dd
DOI
10.21203/rs.3.rs-7241851/v1
Open publication

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Multi-omics analysis identifies lactylation-mediated immune biomarkers in esophageal cancerDOI 10.21203/rs.3.rs-7241851/v1
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