Article

Interleukin-4-mediated regulation of CD25 gene expression in human B lymphocytes

1996-01-01

Abstract excerpt

This thesis describes the regulation of CD25 gene expression by interleukin-4-activated signal transduction pathways in quiescent human B lymphocytes. In particular, the importance of a cAMP-dependent pathway, which down-regulates binding of a putative transcriptionally repressive protein factor from a negative regulatory element in the promoter region of the CD25 gene, is highlighted. CD25 is the alpha chain of t...

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Identifiers and source

Literature Corpus work: 388608f2-f630-524c-8444-20c83e399845
DOI: 10.5525/gla.thesis.71654

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