Article

Regulation of expression of the interleukin-2 receptor alpha chain (CD25) in human tonsillar B lymphocytes

1997-01-01

Abstract excerpt

The Interleukin-2 Receptor α chain (IL-2Rα or CD25) plays an important role in B cell activation since it allows formation of the high affinity IL-2 Receptor and thus permits the B cell to respond to physiological concentrations of IL-2. IL-4 appears to be the sole cytokine which can induce IL-2Rα in human tonsillar B cells. In addition, polyvalent anti-lmmunoglobulin antibodies and anti-CD40 antibodies can cause...

Identifiers and source

Literature Corpus work: e8a75fc5-e9f6-5930-a50e-875acb997c38
DOI: 10.5525/gla.thesis.38915

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Regulation of expression of the interleukin-2 receptor alpha chain (CD25) in human tonsillar B lymphocytesDOI 10.5525/gla.thesis.38915Read

Interleukin 2 leads to dose-dependent expression of the alpha chain of the IL-2 receptor on CD25-negative T lymphocytes in the absence of exogenous antigenic stimulation.Semantic proximity Read

Interleukin-4-mediated regulation of CD25 gene expression in human B lymphocytesSemantic proximity Read

Restricted expression of p55 interleukin 2 receptor (CD25) on normal T cells.Semantic proximity Read

Dysregulation of the interleukin-2 receptor alpha- and beta-chain expression in CD4 and CD8 T cells in HIV infection.Semantic proximity Read

Analysis of the promoter region of the interleukin-2 receptor alpha chain (CD25) gene in human B lymphocytesSemantic proximity Read

[Phenotype expression and production of IL-2 by tonsillar and blood lymphocytes in patients with tonsil pathology].Semantic proximity Read

Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity.Semantic proximity Read

T regulatory cells control T‐cell proliferation partly by the release of soluble CD25 in patients with B‐cell malignanciesSemantic proximity Read