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The vaccine candidate Liver Stage Antigen 3 is exported during <i>Plasmodium falciparum</i> infection and required for liver-stage development

2025-07-19

Abstract excerpt

Plasmodium falciparum remodels infected erythrocytes using exporting effector proteins. Parasites express the aspartyl protease plasmepsin V that processes proteins containing a PEXEL motif and the PTEX translocon to successfully export proteins. During liver-stage infection, PTEX is required for P. falciparum development, but which proteins are exported remain largely unclear, yet they may serve important functi...

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Identifiers and source

Literature Corpus work
3883de37-2571-58d8-a11a-93de18dabedc
DOI
10.1101/2025.07.18.665593
Open publication

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The vaccine candidate Liver Stage Antigen 3 is exported during <i>Plasmodium falciparum</i> infection and required for liver-stage developmentDOI 10.1101/2025.07.18.665593
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