Article

PEXEL is a proteolytic maturation site for both exported and non-exported <i>Plasmodium</i> proteins

2023-07-12

Abstract excerpt

Obligate intracellular malaria parasites dramatically remodel their erythrocyte host through effector protein export to create a niche for survival. Most exported proteins contain a pentameric P lasmodium ex port el ement (PEXEL)/Host Targeting Motif that is cleaved in the parasite ER by the aspartic protease Plasmepsin V (PMV). This processing event exposes a mature N-terminus required for translocation into t...

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Literature Corpus work: 16f5cfff-1c0e-5c06-aa6c-3b32de7df883
DOI: 10.1101/2023.07.12.548774

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