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Article

Uremia causes dysbiosis-mediated periodontal disease

2021-01-25

Abstract excerpt

<title>Abstract</title> <p>It is presently unclear why there is a high prevalence of periodontal disease (PD) in individuals living with chronic kidney disease (CKD). By employing three different models in rats and mice, we demonstrate that experimental uremia causes periodontal bone loss. Uremia alters the biochemical composition of saliva and induces progressive dysbiosis of the oral microbiota, with microbial...

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Literature Corpus work
3833f14b-7ff7-5a71-bce5-dbe3015c11d1
DOI
10.21203/rs.3.rs-143371/v1
Open publication

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