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Gut microbiome signatures precede chronic kidney disease diagnosis in a large canine cohort

2026-08-26

Abstract excerpt

<h4>ABSTRACT</h4> Chronic kidney disease (CKD)-associated dysbiosis is well described after diagnosis, but whether microbial changes precede clinical recognition is unclear. We integrated insurance claims, fecal and oral 16S rRNA profiles, and clinical laboratory data from companion dogs. Among 140,025 dogs, lower gut microbial diversity was associated with incident CKD after adjustment for age, sex and body size...

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Literature Corpus work
ebf88ec9-cc09-580b-8af7-750d344f09f3
DOI
10.64898/2026.08.25.746990
Open publication

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Gut microbiome signatures precede chronic kidney disease diagnosis in a large canine cohortDOI 10.64898/2026.08.25.746990
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