Gut Microbiota and NLRP3 Inflammasome Activation in Hemodialysis Patients: Exploring the Link with Systemic Inflammation

Abstract excerpt

<title>Abstract</title> <p>Background The Nod-Like Receptor Pyrin domain-containing 3 (NLRP3) inflammasome is a critical sensor of bacterial signals and metabolites, initiating an inflammatory response. Chronic kidney disease (CKD) is often accompanied by systemic inflammation, which can be involved with gut dysbiosis. Considering this interplay, we aimed to explore the potential association between NLRP3 inflam...

Topics

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• Acute Kidney Injury Research
• Clostridium difficile and Clostridium perfringens research
• Dialysis and Renal Disease Management
• Diet and metabolism studies
• Gastrointestinal motility and disorders
• Gut microbiota and health
• Metabolomics and Mass Spectrometry Studies
• Traditional Chinese Medicine Studies

Identifiers and source

Literature Corpus work

86e45b07-a797-5df0-8528-92eecd6752c1

DOI

10.21203/rs.3.rs-6248246/v1