Article

De novo missense variants in the PPP2R5D gene associated with Parkinson's disease in Chinese Han population

2021-04-15

Abstract excerpt

<title>Abstract</title> <p>Recent studies have reported an association between PPP2R5D mutations and early-onset levodopa-responsive parkinsonism. However, there was lack of comprehensive analysis of this gene in large Parkinson’s disease(PD) cohort.The aim of this study was to examine the frequency and spectrum of PPP2R5D mutations in a Han Chinese cohort with early- or late-onset PD. We sequenced all 17 exons o...

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Literature Corpus work: 381a2b8a-be4c-5dd8-8ace-39d9da44fe46
DOI: 10.21203/rs.3.rs-423538/v1

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